Long-term and Short-term Mating Strategies: Domain #2 of Male-Female Difference

Long-term and Short-term Mating Strategies: Domain #2 of Male-Female Difference

“…to an extraordinary degree, the predilections of the investing sex —females, determine the direction in which the species will evolve. For it is the female who is the ultimate arbiter of when she mates and how often and with whom.” ~Sarah Blaffer Hrdy, The Women That Never Evolved, 1981

Would You Go to Bed With Me?

In a study on a college campus, confederate men walked up to women, and confederate women walked up to men and said:

“Hi, I’ve been noticing you around town lately and I find you very attractive.”

Then they (eventually) asked:

“Would you go to bed with me tonight?”

All the women said “no,” and were offended, insulted, and just puzzled by the request to go to bed.

Seventy-five percent of the men said “yes.” Many of the men who declined the offer were apologetic, citing previous commitments.

This is an often-cited series of experiments in social and evolutionary psychology conducted by Russell Clark & Elaine Hatfield. These experiments were replicated in France with the same results.

How Receptive are Men versus Women to Sexual Invitations?

In a study by Buss and Schmitt (1993), college men and women rated how likely they were to consent to sex with someone they viewed as desirable if they had known them for only an hour, a day, a week, a month, six months, a year, two years, or five years. Both men and women said they would probably have sex after knowing a desirable potential mate for five years. At every shorter interval, men exceeded women in the reported likelihood of having sex. After knowing someone for only one week, men were positive about consenting to sex.

Women Unlikely to Consent to Sex

Women, in sharp contrast, were highly unlikely to consent to sex. Men were only slightly disinclined to having sex with someone they had known for only one hour; for women, sex after one hour was a virtual impossibility.

Long and Short-term Mating Strategies — Differences Between Men and Women

The predominant theory in evolutionary psychology suggests humans have both long-term and short-term mating strategies. These studies unmask the differences between men and women in their mating strategies.

Second Domain of Differences in Sexual Psychology and Response

This is the second in a series of posts that explain the domains (see Appendix) of difference between men and women in their sexual psychology and response. Tendencies related to short and long-term mating strategies apply to the general population of male and female heterosexuals but do not predict the unique sexuality of a particular man or women. (See introduction to the series: Male-Female Differences in Sexual Psychology and Response.)

This post will explore the following differences:

  1. General psychological factors related to mating strategies
  2. Objectives, costs, and benefits of short-term and long-term mating strategies for men and women
  3. Relative importance of trait preferences for each strategy along three dimensions: physical attractiveness, resources, and character, illustrated by Venn diagrams.
At-a-Glance Summary of this Post
  •  A long-term mating strategy is essentially rooted in commitment and monogamy.
  • A short-term mating strategy allows or prefers casual sex with more than one partner.
  • Women’s predominant mating strategy is long-term vs. short-term by a wide margin.
  • Men’s predominant mating strategy is short-term but their long-term strategy is almost equal for reasons also tied to evolutionary benefits.
  • The human mating economy is primarily fueled (implicitly) by the intersection of men’s short-term mating strategy and women’s long-term mating strategy.
  • Men’s short-term mating strategy is emboldened by their perceived mate value.
  • Women’s short-term strategy is correlated with low self-esteem.
  • Lower mate value men benefit most from a long-term strategy.
  • High mate value women (commonly with high self-esteem) choose a long-term strategy and benefit most from that strategy.
  • Men have lower standards for short-term mates, requiring almost no traits other than physical attractiveness.
  • Women’s short-term strategy emphasizes physical stature of the man, with some concern for resources and character.
  • Women’s short-term strategy, while secondary, reveals complex motivations and is used to secure resources, access better genes, switch mates, and sometimes secure a long-term partner.
  • Men’s short-term strategy gives great emphasis to physical attractiveness, has a small concern for character, and no concern for resources.
  • Men’s long-term mating strategy has character requirements, some resource considerations, and an emphasis on physical attractiveness.
  • Women’s long-term strategy has a great need for resources and character, with physical attractiveness prioritized in a third position. Resources and character are often subject to trade-offs in mate selection.
  • Long-term and short-term mating strategies operate as concurrent functions (like dual processing switches) sensitive to context and environmental conditions.
  • Female choice in mate selection is the most powerful force on the planet – determining the mating strategies of both sexes.
General Sex Differences in Long-term and Short-term Mating Strategies

The above studies underscore several differences in male-female sexual psychology and response, as noted in: Dynamics in the Mating Economy: Domain #1 of Male-Female Difference.

  • Women have the psychology of choice and an abundance of sexual attention during their reproductive years; men mostly do not have choice or an abundance of mating opportunities.
  • Men (mostly) have the psychology of sexual scarcity.
  • Women have the psychology of caution and fear — sexual inhibition and “brakes” on sexual activity and the experience of risk. Women fear being physically hurt, left to fend on their own with a child, or suffering reputational damage.
  • Women are prone to have regret or guilt about what they did in the sexual and mating realm.
  • Men are prone to have guilt and regret about what they did not do.
  • Men fear being humiliated and rejected.
  • Men are driven by a spontaneous, initiating sexual psychology (spontaneous desire) and women are characterized by a cautionary, “response desire.”

Mating Strategies Introduction

“Today’s dating scene has become a global uncontrolled experiment in competing mating strategies. Men and women are locked in a run-away arms race of male sexual escalation tactics vs. female commitment escalation tactics. Science-minded singles have a new self-consciousness as fitness displayers, mate choosers, gene replicators, and social primates.” ~ Evolutionary Psychologist, Geoffrey Miller (YouTube – 2019)

Long-term Mating Strategies

A long-term mating strategy for men involves attracting and securing a mate who will provide sexual fidelity. A long-term mating strategy for women seeks sexual fidelity and provision of resources and protection of children over time. Women have predominantly a long-term mating strategy (and sex “drive”) that most often seeks a single-sex partner who is committed to her and the potential offspring that might result from their mating. A women’s long-term strategy creates caution and selectivity in accepting male advances. The desired benefits of a woman’s long-term strategy influence male sexual access and thus much of male behavior. (See Mate Selection Science.)

Short-term Mating Strategies

A short-term mating strategy attempts to maximize immediate sexual access and sexual partners. Men have evolved with mostly a short-term-mating strategy (and sex “drive”) but also employ a long-term strategy for several evolutionary advantages. A man’s short-term mating strategy fuels desire for contact with women for any possible chance of a romantic or sexual encounter. Although much less predominant, a woman’s short-term mating strategy may include a complex set of motivations. (See Why Women Have Sex.)

Dual Processing Switches

Long-term and short-term strategies for men and women operate as concurrent functions sensitive to context and environmental conditions. They are not binary operations but more like dual processing switches with a range or “volume” on each at any moment in time. They may function in parallel like a thermostat, modulating the influence of other mode to keep a particular sexual personality in balance or at its “set” point. Sexual strategies by men and women are influenced by age and especially a woman’s fertility window.

Big Cojones — Evidence of Short-term mating

Evidence of short-term mating is seen by the size of human male testes; they are larger than the highly monogamous gorillas and orangutans, but smaller than the more promiscuous baboons, bonobos, and common chimpanzees. Bigger testes mean more sperm competition and more short-term mating.

Sperm Volume

Also, sperm volume increases related to the amount of time a couple has been apart since their last encounter. This increase in sperm insemination is precisely what is expected if humans had an ancestral history of casual sex and marital infidelity. The fact that men carry a physiological mechanism that elevates sperm count when their wives may have had opportunities to be unfaithful points to an evolutionary history in which humans had extramarital affairs at least some of the time.

 
“Collision” of Strategies

The human mating economy is primarily fueled (implicitly) by the intersection of men’s short-term mating strategy and women’s long-term mating strategy (See Human Mating Strategies). This “collision” of a man’s short-term mating strategy and a woman’s long-term mating strategy continues to shape gender-specific sexual behavior in modern times and causes more selectivity, caution, and different sexual responses by women as compared to men. Mating strategy “conflict” is resolved by accommodation and negotiation in a process of mate value sorting within the mating economy. It is highly dependent upon individual context. Desire is mitigated by costs, benefits, and availability for both sexes.

Diagram #1: “Collision” of Mating Strategies

venn diagram: collision_of_mating_strategies
Subset Strategies

Humans also have “subset” mating strategies or mating behaviors that intersect with basic long and short-term strategies, including serial mating and extra-pair copulation (EPC) – i.e. infidelity or consensual non-monogamy. Which mating strategy is adopted very much depends on individual mate value. Those higher in mate value can more easily implement their preferred mating strategy. In general, higher mate value women focus even more on a long-term strategy and higher mate value men may focus even more on a short-term strategy. Mating strategy can also be influenced by the sex ratio in the local mating pool and operation of social/cultural norms in the local environment.

Humans Employ Strategic Pluralism

Ultimately, what people want in a long-term mate can be quite different from what they want in a short-term mate. Humans employ “strategic pluralism” — a variety of strategies and tactics when it comes to mating. There are multiple routes to mating success.

Women’s Long-term Strategy

Women’s long-term mating is driven by genetic characteristics and interests of our species: internal fertilization, an extended period of gestation, prolonged infant dependence on mother’s milk, and the need for relatively “high” male parental investment compared to other primates. In addition to protection and a provision of resources, a woman’s long-term strategy seeks character traits that ensure stability and loyalty to her and her children over the long-term.

Trade-offs Between Resources and Character

What is often more salient in female mate selection and relationship satisfaction is the tension between the two preferences inside the female long-term strategy: resources and character. A woman’s long-term mating strategy often involves ambivalence and internal confusion related to her desire for a mate with resources and status, and her preference for loyalty, kindness, intelligence, and character traits for parenting. (See “trade-off boundary” on diagram below.) In America, resources usually win this game of mate selection preference, often with rationalization and denial about the lack of optimal character.

Diagram #2: Women’s Long-term Mating Strategy

Venn diagram: women's long-term mating strategy

Benefits of Women’s Long-term Mating Strategy

  • Significant resources from mate
  • Parental investment
Costs of Women’s Long-term Mating Strategy
  • Restricted sexual opportunity
  • Sexual obligation to mate

The benefits far outweigh the costs and have pre-eminent value in female mate selection — and thus overall power to influence sexual access and all domains of male behavior.

Women’s Short-term Strategy

Women are found to prefer features related to muscularity, strength, fitness, and masculinity – traits associated with symmetry, in their short-term mates. They also look for stable character traits (minimal levels of generosity and kindness) and a fair amount of resources. While the following gives considerable attention to the complexities of a woman’s short-term strategy, it bears repeating that this strategy is not dominant in female mate selection; it is secondary and selective.

Diagram #3: Women’s Short-term Mating Strategy

venn diagram: women's short-term mating strategy
Benefits of a Woman’s Short-term Strategy

Women have a short-term mating strategy that brings several benefits. According to David Buss (Evolutionary Psychology, The New Science of the Mind, 1999), there are three classes of benefits (among a few other hypotheses) that are supported by research:

  1. Resource acquisition. Women could engage in short-term mating for the immediate exchange of meat, goods, or services. Ancestral women may have also engaged in short-term mating in order to obscure the paternity of her offspring (“paternity confusion”) and elicit resources from more than one man. In addition, short-term mating may have brought protection (a resource) from other males when the primary mate was not present.
  2. Genetic benefits. Short-term mating potentially brings enhanced fertility. It may also bring superior or diverse genes from a high-status male, thus giving offspring a better chance of survival against environmental change. Also, the “sexy son” hypothesis suggests that male progeny of such men are very attractive to women in the next generation, thus securing a positive genetic legacy.
    • Physical Stature Equals Genetic Fitness. Women’s prioritization of physical features in short-term partners is consistent with strategic pluralism theory that says women may seek genetic fitness in short-term partners. (Gangestad and Simpson, 2000). According to this “good genes” theory (Thornhill and Gangestad, 1993), women are attracted to men who effectively advertise having genes that are resistant to local pathogens.
    • Ovulation and Short-term Mating Success. Research has found that women value such characteristics (including the scent of symmetrical men) even more around the time of ovulation. As a result, symmetrical and muscular men have greater short-term mating success compared to their relatively asymmetrical and non-muscular peers. They have more sexual partners and are more desirable as affair partner.
  3. Mate Switching Hypotheses. While preferences for traits associated with high-testosterone (muscularity, strength and facial symmetry) tend to support the hypothesis that women seek genetic benefits in short-term mating, recent research and DNA evidence has cast some doubt on this as a motivation and has drawn more attention to the “mate switching hypothesis.” (See Mate Switching Hypothesis).

David Buss (Evolutionary Psychology, The New Science of the Mind, 1999) identifies three reasons for a woman’s short-term mating strategy (infidelity or extra-pair copulations) that confirm a mate switching hypothesis.

Hit the Road Jack

One study found that extra-pair mating made it easier for a women to break up with their current partner — what Buss calls “mate expulsion.” David Buss and Cindy Meston report (Why Women Have Sex, 2009) that women have affairs to test the waters to see if there is someone better out there for them, in an attempt to “trade-up” for a better partner. Women have affairs if they think their relationship may be dissolving. And women cultivate “back-up mates.” As Buss likes to joke in quoting a female research participant, “men are like soup; you always want to have some on the back burner.”

From a Short “Flight” to a Long “Flight”

According to “sexual strategies theory” (Buss and Schmitt, 1993), by being open to short-term relationships, women can increase their options for long-term ones. They can solicit the interest of many men and use this wider net to evaluate long-term mates, or they may be able to turn short-term relationships into long-term ones. If women use short-term mating to assess or attain long-term relationships, they may prioritize the same traits in short-term partners that they prioritize in long-term partners.

More Clues to Mate Switching and Sex Differences

There are other clues to explain the infidelity (short-term mating strategy) of women as reported by Buss –clues that fortify a mate switching objective.

  1. Women who are sexually or emotionally unhappy have affairs. This is not true for men. Men do not often report marital unhappiness as a reason for an affair. According to Buss, men can be relatively happy in their marriage and still have affairs. The issue of emotional dissatisfaction appears to be specific to women.
  2. 70% of women become emotionally involved with or fall in love with their affair partner. In contrast, only about 30% of men do.
  3. As stated above, qualities desired by women in an affair partner are often similar to the qualities desired in a long-term mate. Women want character traits (e.g. kindness) and resources in an affair partner, just not as much as in a long-term mate. This is not true for men. For example, women usually want intelligence in an affair partner. For men, intelligence in an affair partner is mostly irrelevant. Desiring the same qualities in an affair partner further supports a view that the female long-term mating strategy is significantly more adaptive in evolution than the short-term mating strategy.
Self-esteem in Women

Studies have shown that a woman’s self-esteem is a significant predictor of short-term-mating. Women scoring low on self-esteem tended to have a greater number of sex partners, one-night stands, and a preference for short-term sexual relationships.

Costs of Women’s Short-term Strategy
  • Risk of a sexually transmitted disease
  • Risk of pregnancy
  • Reduced value as long-term mate
  • Greater risk of physical and sexual abuse
  • Risk of withdrawal of resources from husband

While the benefits noted above seem compelling, the costs of a woman’s short-term mating strategy far outweigh the benefits and produce a “response desire” and “braking” pattern of female sexual response. These costs directly influence female sexual response and sexual psychology. (See Spontaneous and Response Desire – the Underbelly of Heterosexual Mating.)

Men’s Short-term Strategy

“There seems to be no question but that the human male would be promiscuous in his choice of sexual partners throughout the whole of his life if there were no social restrictions. The human female is much less interested in a variety of partners.” ~ Alfred Kinsey

Evolutionary adaptation has dictated a preference by men for a short-term mating strategy. Trivers’s (1972) theory of parental investment and sexual selection provides a powerful reproductive basis for expecting sex differences. Men, more than women, are predicted to have evolved a greater desire for casual sex and a variety of partners. The same act of sex that causes a woman to invest nine months of internal gestation obligates the man to practically no investment.

Premium On Female Beauty

Men’s short-term strategy puts an immense premium on physical beauty and fertility. Character traits required of a woman are minimal (i.e. “don’t be dangerously crazy”) and resources are not required at all. Men’s short-term strategy is more predominant than their long-term strategy, but the difference is less pronounced behaviorally in modern times.

Diagram #4: Men’s Short-term Mating Strategy

venn diagram: men's short-term mating strategy
Restraints on Men’s Short-term Mating Strategy

Although men could potentially conceive more offspring if they were promiscuous instead of monogamous, there may have been at least two restraining factors of evolution against male promiscuity. Reproductive success depends on the survival of one’s offspring. Children have a better chance of survival if two parents contribute. Men who were highly promiscuous may not have been able to support all their offspring, and thus may not have been as genetically successful as more monogamous men.

Women Have to Consent

As suggested by Roy Baumeister and Dianne Tice (The Social Dimension of Sex, 2001), a second possible restraining factor on male promiscuity is an obvious one: the question of whether a male can get a lot of potential mates if females won’t consent to mate with him.

Promiscuous Male At Possible Disadvantage

Men not predisposed to mate in long-term relationships might not have left enough offspring for a totally promiscuous genetic tendency to proliferate. According to Baumeister and Tice, males thus evolved to mate in long-term relationships to raise their children to adulthood, and also evolved a tendency to be more open than females to a wider variety of mating opportunities. Perhaps this greater need for compromise between monogamy and promiscuity can also explain why men have a greater variety of sexual practices and interests than women.

Put A Ring On It

David Buss suggests (Evolutionary Psychology, The New Science of the Mind, 1999), that men, even in ancestral times, who failed to commit might not have attracted any women at all. Women’s requirement for consenting to sex could have made it costly for men to pursue a short-term strategy exclusively. In the economics of reproductive effort, the costs of not pursuing a permanent mate may have been prohibitively high for most men.

High Mate Value Men Like Short-term Mating

High mate value men (on the “Self-perceived Mating Success Scale”) tended to have sex at an earlier age, a greater number of sex partners, and more sex relative to their lower mate-value counterparts. And high mate value men scored higher on the “Sapiosexuality Inventory” suggesting that they are pursuing a short-term mating strategy. These are measures of the holy grail of sexual turn-on for women: self-confidence. This is what “cocky” really means. (BTW, penis size does indeed contribute to this self-confidence — to being “cocky.” (See Undiscussables.)

Men Lower Their Standards

Buss and Schmitt (1993) found that men desire more partners and lower their standards for short-term mating. Men in this study expressed lower standards than women on forty-one of the forty-seven characteristics named as potentially desirable in a casual mate. For brief encounters, men required a lower level of charm, athleticism, education, generosity, honesty, independence, kindness, intelligence, loyalty, sense of humor, sociability, wealth, responsibility, spontaneity, cooperation, and emotional stability.

Closing Time Phenomenon

Relatedly, men shift perceptions of attractiveness near closing time in a singles bar regardless of how much alcohol they have consumed. With this “closing time phenomenon,” women just look better and better as the night wears on. In contrast to men, most women can obtain a desirable temporary mate without having to relax their standards at closing time.

Sex Ratio Effect on Short-term Mating for Both Sexes

Men shift to brief encounters when more women are sexually available (positive sex ratio), satisfying their desire for variety. Correlated to that, women on college campuses today will shift toward more short-term mating because the surplus of women causes more intra-sexual competition. When there is a surplus of men, in contrast, both sexes shift toward a long-term mating strategy marked by stable marriages and fewer divorces.

Benefits of Men’s Short-term Strategy
  • Potential to reproduce; more sex partners
  • No parental investment
Costs of Men’s Short-term Strategy
  • Risk of sexually transmitted diseases
  • Some resource investment
  • Less protection for genetic children
  • Acquiring a reputation as a womanizer
  • Suffering violence from husbands, brothers or fathers
  • Retaliatory affairs by wives or a costly divorce

The benefits of the male short-term mating strategy have shaped the evolution of male neurology and physiology and influenced male behavior, especially sexual initiation and intra-sexual competition. But costs do mitigate this strategy, especially in modern times.

Men’s Long-term Strategy

For long-term mates, men still put a premium on physical beauty and markers of health and fertility for initial attraction. Buss and Schmitt (1993) studied 37 cultures and confirmed the universal desire for physical attractiveness in a long-term mate. But men also want a woman who is faithful and kind. Resources are considered but are usually a distant third in importance. As stated above, men who are willing to commit to a long-term relationship have a wider range of women from which to choose.

Marriage in the U.S. Favors Men With Resources

As discussed in Dynamics in the Mating Economy: Domain #1 of Male-Female Difference, marriage patterns in modern America confirm the fact that men with resources are most able to actualize their preferences.

Diagram #5: Men’s Long-term Mating Strategy

venn diagram: men's long-term mating strategy
Benefits of Men’s Long-term Strategy
  • Increased paternity certainty
  • Improved social competitiveness of children
  • Sexual and social companionship, especially for “beta” males
Costs of Men’s Long-term Strategy
  • Restricted sexual opportunities
  •  Heavy parental investment
  • Heavy relationship investment

The benefits of men’s long-term mating strategy tend to outweigh the costs in most cultures in modern times. Pair-bonding and relative monogamy is the norm in most modern societies.

References

Buss, D. M., (1999). Evolutionary Psychology, The New Science of the Mind.

Buss, D. M. & Schmitt, D.P. (1993) “Sexual strategies theory: An evolutionary perspective on human mating.” Psychological Review, 100, 204-232.

Clark, R. D. & Hatfield, E. (1989). “Gender differences in receptivity to sexual offers.” Journal of Psychology and Human Sexuality, 2, 39-55.

Dibble, et al (2015, June 11). “Simmering on the back burner: communication with and disclosure of relationship alternatives.” Communication Quarterly, 63(3), 329-344.

Gangestad, S.W. & Simpson, J.A. (2000). “The evolution of human mating: Tradeoffs and strategic pluralism.” Behavioral and Brain Sciences, 23, 573-587.

Li, P. (2008). “Intelligent Priorities: Adaptive Long- and Short-term Mate Preferences,” in Mating Intelligence, eds., Geher, G., & Miller, G.

Thornhill, R., & Gangestad, S..W. (1993). “Human facial beauty: Averageness, symmetry and parasite resistance.” Human Nature, 4, 237-269.

Trivers, R. L. (1972). “Parental investment ad sexual selection.” In B. Campbell (Ed.), Sexual Selection and the Descent of Man, (pp.136-179).

Appendix

 
Domains of Male-Female Differences in Sexual Psychology

1. Behavioral dynamics in the mating economy

2. Long-term vs. short-term mating strategies

3. Trait preferences and priorities for mate selection

4. Physical attraction and perceptions of beauty

5. Concordance between physiological response and psychological desire

6. Spontaneous desire vs. response desire

7. Sex and love-making that fuels desire

8. Accelerator vs. brake: sexual excitation and inhibition systems

9. Brain structures: sexual pursuit and visual stimuli

10. Hormonal differences

11. Variety and novelty

12. Sexual mentation and “sex drive”

13. Influence of context

14. Female competing intentions and imposed double bind 

15. Sexual orientation (and preference) fluidity and response variability

16. Orgasm – purpose and characteristics

17. Meta emotions

18. Romance and desire, together and apart

19. Psychology of monogamy

20. Infidelity – reasons and response

21. Jealousy – triggers, tactics, and consequences

22. Sexual fantasies

 

*Assumptions of Mating Straight Talk
  • Men and Women have similarities as human beings, and aggregate differences from each other, that are primarily a function of biology and evolutionary adaptation. Our similarities do not often cause conflict. But our differences, and the denial of those differences, often cause “trouble”.
  • Men and Women have differences that we must acknowledge and understand in order to have satisfying heterosexual (romantic and sexual) relationships.
  • Men and Women have differences that we must acknowledge and understand in order to bring clarity to the “politics” of sex and gender.
  • Men and Women need “straight talk” (radical honesty) in order to uncover and accept our differences.
  • Men and Women need straight talk about our differences in order to empower one another for co-creative relationships.

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Male-Female Differences in Sexual Psychology and Response

Male-Female Differences in Sexual Psychology and Response

Over the millennia, men and women have evolved with different objectives and strategies of sexual psychology and response – strategies related to choosing a mate, reproduction, and parental investment. For the next several months, this blog space will address twenty-two “domains” of difference in sexual psychology and response between cisgender men and women with an emphasis on a heterosexual orientation.* (See “Assumptions” below.)

Here is a narrative summary of these differences followed by a list of the twenty-two domains. There is overlap and synergy between the domains but the underlying distinctions are clarifying. These differences are based on statistical aggregates of all men and women from authoritative research studies and cannot predict the unique sexuality of a particular man or woman.

General Differences between Men and Women in Sexual Psychology and Response
  • Women have their own unique sexuality, like a fingerprint, and vary more than men in anatomy, sexual response, sexual mechanisms, and the way their bodies respond to the sexual world. Women vary more widely from each other and change more substantially over their lifetime than do men.
  • Women are less likely to have alignment (“concordance”) between their genital response and their subjective arousal; this causes confusion and misunderstanding for women and their male partners. Men have dramatically more concordance between their genital response and subjective arousal.
  • All sex happens in context. Women are more context-sensitive than men and all external circumstances of everyday life influence the context surrounding a woman’s arousal, desire, and orgasm.
  • Women’s sexual functioning is more influenced by their internal brain state — how they think and feel about sex. Judgment, shame, stress, mood, trust, body image, and past trauma are more influential on a woman’s sexual well-being.
  • Men and women have significantly different hormones and some variations in brain structure. Differences caused by the amount of testosterone cannot be overstated.
  • Men and women differ in visual orientation for physical attraction and the traits preferred in a mate.
  • Human sexual response consists of a “dual control” system with an excitation mechanism (“accelerator”) and an inhibition mechanism (“brake”). Men are accelerator-dominant and women are brake-dominant.
  • Related to differences between the sexual “accelerator” and “brake,” men operate primarily from “spontaneous desire” triggers and women operate primarily from “response desire” triggers.
  • Men sell (mostly) and women buy (mostly) in the mating economy; this is the predominant evolutionary dynamic. The psychology of the sexual initiator and pursuer is vastly different than the psychology of the one pursued and the one who chooses among her pursuers.
  • The psychology of male intra-sexual competition is quite different than the psychology of female intersexual selection (preferential mate choice.) Also, women’s intra-sexual competition (women competing against each other) for male attention is a different behavioral phenomenon than male-on-male competition.
Domains of Male-Female Differences in Sexual Psychology

1. Behavioral dynamics in the mating economy
2. Long-term vs. short-term mating strategies
3. Trait preferences and priorities for mate selection
4. Physical attraction and perceptions of beauty
5. Concordance between physiological response and psychological desire
6. Spontaneous desire vs. response desire
7. Sex and love-making that fuels desire
8. Accelerator vs. brake: sexual excitation and inhibition systems
9. Brain structures: sexual pursuit and visual stimuli
10. Hormonal differences
11. Variety and novelty
12. Sexual mentation and “sex drive”
13. Influence of context
14. Female competing intentions and imposed double binds
15. Sexual orientation (and preference) fluidity and response variability
16. Orgasm – purpose, and characteristics
17. Meta emotions
18. Romance and desire, together and apart
19. Psychology of monogamy
20. Infidelity – reasons and response
21. Jealousy – triggers, tactics, and consequences
22. Sexual fantasies

Each domain will be examined as a distinct phenomenon of difference although some will be addressed as correlated or parallel in physiological or psychological response. This blog series will not necessarily run continuously – as other topics (some in a series, some not) will also be posted.

Thanks for reading what is coming to Mating Straight Talk. Comments are encouraged!

*Assumptions of Mating Straight Talk
  • Men and Women have similarities as human beings, and aggregate differences from each other, that are primarily a function of biology and evolutionary adaptation. Our similarities do not often cause conflict. But our differences, and the denial of those differences, often cause “trouble”.
  • Men and Women have differences that we must acknowledge and understand in order to have satisfying heterosexual (romantic and sexual) relationships.
  • Men and Women have differences that we must acknowledge and understand in order to bring clarity to the “politics” of sex and gender.
  • Men and Women need “straight talk” (radical honesty) in order to uncover and accept our differences.
  • Men and Women need straight talk about our differences in order to empower one another for co-creative relationships.

Please Note: Your comment may take up to 12 seconds to register and the confirmation message will appear above the “Submit a Comment” text. 

Spontaneous and Response Desire – the Underbelly of Heterosexual Mating

Spontaneous and Response Desire – the Underbelly of Heterosexual Mating

 

John met Sarah at a happy-hour event. She was surrounded by a group of men, but John got some eye contact from her and shared a quick introduction and small talk.  It was apparent she was not “with” any of these men, although each one was interested in her.  John was enamored by Sarah’s bright eyes, her smile, her gestures, her voice – by everything about her. He felt compelled (an urgency in his body) to get a moment with her as she walked toward the door to depart.  He gave her his card.  (He knew that was lame.) Of course, she did not call him.  He saw her weeks later at the same event.  He asked for her number and declared his interest.  She said she “was not dating right now.” John expressed understanding and acceptance. But he did not really understand if Sarah was just not into him or if this was actually a “bad time” (whatever that meant) for her.  John had done his part to initiate but did not know Sarah’s “situation” or what she was actually thinking and feeling.  And he never would.

What Are ‘Spontaneous’ and ‘Response’ Desire?

“Spontaneous” and “response” desire are research terms related to the sexual psychology of men and women.  They reflect behavioral expressions of biological sex differences (hormones and brain), evolutionary mating strategies, sex “drive” differences, differences in sexual “context” setting, and functioning of the modern-day dating and mating economy.

When the spontaneous desire of men encounters the response desire of women, misunderstanding and frustration may ensue.  This blog explores research on sexual desire by Emily Nagoski* (Come As You Are, 2015) and is a companion to the blog post “Is Your Sexual Foot on The Accelerator or Brake?”   I will address issues of spontaneous vs. response desire related to long-term committed partners and supply and demand in the mating economy for initial mate selection and briefly return to John and Sarah before concluding.  But first, let’s revisit some of the science.

Sexual Excitation System (SES) and Sexual Inhibition System (SIS)

Emily Nagoski suggests both men and women have an excitation system (accelerator) and inhibition system (brake) for sexual activity.   She calls this the “dual control model.”  Think of this dual control as biological mechanisms for approach and avoidance.

Men Operate From Their Accelerator

Men operate primarily from their accelerator, or sexual excitation system (SES), constantly scanning the environment for anything sexually relevant.  The SES turns-on with anything a man sees (especially), hears, smells, tastes, or imagines.  The SES operates proactively — it approaches, pursues, and initiates spontaneously.

Women Are “Brake” Dominant

 The inhibition system or brake (SIS), in contrast to the SES, notices all potential threats in the environment and sends a signal to turn-off.  It is associated with fear of consequences and self-consciousness.  Women are decidedly SIS-dominant.  They respond to sexual opportunities only in the right context and when safety is assured.  They are quite content to rest in a cautious or neutral zone until the right stimulus is presented.  Out of sight, out of mind is the default position of response desire.

Spontaneous Desire is the Signature Feature of the Male Sex Drive

“Spontaneous desire” happens when the SES is fully activated.  The SES fuels spontaneous sexual pursuit with a sense of urgency and eagerness.   Male sexuality is “accelerator-dominant” and spontaneous by nature; it reacts, more than women, to sexually relevant stimuli independent of context and more commonly initiates.  Spontaneous desire is the signature feature of the male sex drive, fueled by testosterone and brain structures.  (See future blogs for further discussion of sex drive, sexual thoughts, and fantasies.)

When Arousal Meets a Great Context

“Response desire” occurs when one is willing to receive sexual interest although not initially feeling desire or sexual arousal.  The SES accelerator system is quiet; the SIS braking system is alert but not overly triggered. With sufficient sexual stimuli and appropriate context, response desire allows one (usually a woman) to move from a place of neutrality to being aroused and desirous of a sexual connection.   Because women are more “brake-dominant” in their sexual response, their desire more likely happens, in Nagoski’s words, “when [physiological] arousal meets a great context.”  For many women, subjective desire comes after physiological arousal, not before.  Rosemary Basson (author and Director of the University of British Columbia Sexual Medicine Program) says for many women, desire is not the cause of love-making, but rather the result.

Eighty-Five Percent of Women Are Response-Desire Dominant

According to Nagoski, 30 percent of women never experience spontaneous desire for sex, while 75 percent of men mostly experience spontaneous desire.   She says 55 percent of women experience a relative combination of spontaneous and response desire but ultimately concludes (Come As You Are, p. 307) that 85 percent of women are response-desire dominant.

Context Is Everything for Women

Nagoski says context for women is made of two things:  

1) the circumstances of the present moment – whom you are with, where you are, whether the situation is novel or familiar, risky or safe, and

2) a woman’s brain state in the present moment:  whether she is relaxed or stressed, trusting or not, loving or not, at that moment. 

“The evidence is mounting that women’s sexual response is more sensitive than men’s to context, including mood and relationship factors, and women vary more from each other in how much such factors influence their sexual response.”  (Come As You Are, p.  75).  For women, a great context can create subjective arousal; a bad context can prevent it entirely.

Desire Patterns in Long-term Relationships

The “collision” or “collaboration” of these two desire patterns can create interesting challenges in heterosexual sexual relating, especially in sustaining desire in long-term monogamous relationships.

For maintaining mutual desire in a long-term monogamous relationship, Esther Perel, (author of Mating in Captivity and leading expert in couple’s psychotherapy) recommends developing autonomy “inside of” the relationship in order to create a space for “wanting” what you don’t have.   John Gottman, in contrast, recommends (The Science of Trust) deepening intimacy as a doorway to the erotic life in a long-term monogamous relationship.   Perel says “build a bridge to cross” fueled by “wanting” and Gottman says “build a bridge together” fueled by “having.”

Increase Activation of Accelerator and Decrease Activation of the Brake

Nagoski says either of these strategies may accomplish the same overall goal:  increasing activation of the accelerator and decreasing activation of the brake.  The goal of both approaches is to sustain curiosity.  Perel suggests we sustain curiosity about our partner when we view them from a distance.  Gottman suggests we sustain curiosity about the nature of pleasure in the context of commitment.

Take Control of the Context

It is clear that passion does not happen automatically in a long-term relationship. But passion can happen if the couple takes deliberate control of their context.  Neither the strategy of distance nor the strategy of deepening intimacy by itself will nullify the foundational, biological difference between spontaneous male desire and response-oriented female desire.

Spontaneous and Response Desire in the Brain

Differences in brain structure between men and women relate to the spontaneous and response desire systems.  Men, in general, have a higher baseline of activity in the older part of the brain, the limbic system, which makes them particularly alert during the first stage of seduction, according to the renowned physician and author, Marianne Legato (Why Men Die First).

Area of Sexual Pursuit is 2.5 Times Larger In Males

The medial preoptic area (MPOA), found in the hypothalamus, is related to sexual pursuit and is 2.5 times larger in males, according to neuropsychiatrist, Louann Brizendine (The Male Brain).  Men also show greater activity in the visual cortex when perceiving erotic pictures, reflecting a gender-specific visual mechanism for sexual selection.

Female Amygdala and Cautious Sexual Response

The brain’s danger and alert system is the amygdala.  While larger in males, the female amygdala seems to be more sensitive to the fear of consequences, modulating a more cautious sexual response.

Fear of Punishment and Sexual Anxiety in the Female Brain

Another part of the brain, the anterior cingulate cortex (ACC), creates a more response-dominant neurological foundation for women.  According to Brizendine, the ACC is the worrywart, fear-of-punishment area, and center of sexual performance anxiety.  It weighs options, detects conflicts, and motivates decisions.  The ACC is also the area for self-consciousness; the ACC is bigger in women.

Spontaneous and Response Desire is Predicted in Human Mating

The difference in male and female desire patterns is extremely relevant to the operation of the dating and mating economy.  Spontaneous desire and response desire are aligned with the short-term mating strategy of men, the long-term mating strategy of women (respectively), and the biological foundation of the sexual accelerator and brake.   Spontaneous desire for men and response desire for women are predicted by human mating strategies as defined in the fields of evolutionary psychology and biological science.

A man’s short-term mating strategy fuels desire for contact with women for any possible chance of a romantic or sexual encounter.   A women’s long-term strategy creates caution and selectivity in accepting male advances.  The reasons for this evolutionary adaptation are central tenets of mate selection science.   (See Human Mating Strategies and What is Mate Selection Science? pages.)

Supply and Demand of Spontaneous and Response Desire

Men (mostly) sell.  Women (mostly) buy.  In the human mating economy, the buyer (female chooser) significantly controls the marketplace; men spontaneously pursue, women respond when ready.  The difference between buyer and seller in the sexual marketplace determines motivation, behavior, and the experience of sexual scarcity or abundance.

Sex is (Relatively) an Abundant Resource for Women

Sex for most women (during their fertile years) is an abundant resource; it is not in short supply.  It is a need (subject to self-imposed selection preferences) that can almost always be met.  Therefore, there is no need to attend to it (out of sight, out of mind).  There is no need to respond to any particular man if conditions are not perfect and that man is not preferred (in that moment) over other men available in her dating pool.   At another moment in time, Sarah might respond to John. 

Conclusion

Sexual relating between men and women often hinges on the “dance” between spontaneous desire and response desire – the “undercurrents” of strategy and preference in dating and mating.   Desire patterns are biologically based with evolutionary roots (human mating adaptations for reproduction and survival of children).  Understanding sex differences in spontaneous and response desire is a pathway for awareness, empathy, and behavior change that will improve heterosexual relationships.

Notes

Emily Nagoski is the former Director of Wellness Education at Smith College where she taught Women’s Sexuality.  She is a respected author and expert in the field of sexuality — writing, speaking, and training internationally.

If you are tracking along with these blogs (in addition to reading pages on the main menus!), you will notice I have cited (so far) male-female differences related to:

  • subjective vs. physiological arousal,
  • sexual excitation vs. inhibition,
  • spontaneous vs. response desire,
  • sex “drive,” 
  • influence of situational context, and
  • overall mating strategies.

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Is Your Sexual Foot on the Accelerator or Brake?

Is Your Sexual Foot on the Accelerator or Brake?

Men and women are different. Their “sexual engine” makes different use of the accelerator and brake. Author, sex researcher, and professor of women’s sexuality, Emily Nagoski, calls this the “dual control model” (Come As You Are, 2015). This model explains aspects of the biological and psychological difference between male and female sexuality and what we need to know to have sexual self-confidence and empathy for our partners.

Accelerator vs. Brake

The central sexual response mechanism in the brains of men and women consist of two universal components – a sexual accelerator and a sexual brake.

This dual control model consists of two parts:

  1. The Sexual Excitation System (SES) or “accelerator” of sexual response receives information about sexually relevant stimuli in the environment. It sends signals from the brain to the genitals to “turn-on”. The SES constantly scans the “context” (including thoughts and feelings) for things that are sexually relevant. With the SES, anything you see, hear, smell, taste, or imagine might send a “turn-on” message.
  2. The Sexual Inhibition System (SIS) is the sexual “brake.” This system notices all potential threats in the environment (such as STI transmission, unwanted pregnancy, social consequences of sexual activity) and sends signals to “turn off”. Nagoski calls this the sexual “foot brake.” It is primarily associated with the fear of consequences. There is also a second brake, more akin to a handbrake, associated with a fear of performance failure, like worry about not having an orgasm. “If you try to drive with the handbrake on,” says Nagoski, you might be able to get where you want to go, but it’ll take longer and use a lot more gas” (Come As You Are, p. 49).
For Arousal — Activate the Accelerator and Deactivate the Brake

Arousal (psychological desire) happens with activation of the accelerator and deactivation of the brake. The former is more salient for men, the latter more important for women. Male sexuality is accelerator-dominant because the SES scans for female attributes that are cues of fertility. The SES (in men) is the pursuer and the initiator. Women’s brake system comports with the evolutionary agenda for a cautious choice of a mate and a need for safety.

Accelerator and Brake in the Brain

Differences in brain structure between men and women are related to the male-dominant accelerator system and the female-dominant brake system.

Men, in general, have a higher baseline of activity in the older part of the brain, the limbic system, which makes them particularly alert during the first stage of seduction, according to Marianne Legato* (Why Men Die First). The medial preoptic area (MPOA), found in the hypothalamus, is related to sexual pursuit and is 2.5 times larger in males, according to neuropsychiatrist Louann Brizendine (The Male Brain). Men also show greater activity in the visual cortex when perceiving erotic pictures, reflecting a gender-specific visual mechanism for sexual selection.

Female Amygdala is More Sensitive to the Fear of Consequences

The brain’s danger and alert system is the amygdala. While larger in males, the female amygdala seems to be more sensitive to the fear of consequences descriptive of the braking system.

Brain’s Worry Center is Bigger in Women

Another part of the brain, the anterior cingulate cortex (ACC), is also involved in “braking.” According to Brizendine, the ACC is the worrywart, fear-of-punishment area, and center of sexual performance anxiety. It weighs options, detects conflicts, and motivates decisions. The ACC is also the area for self-consciousness (the “handbrake”). The ACC is bigger in women. In addition to a less active ACC in men, testosterone decreases worry about punishment and reduces the strength of a sexual brake and fortifies the sexual accelerator.

Women Put On the Brakes

For women, in both ancient and modern times, safety is a powerful need that activates the sexual brake: fear of being killed, being raped, getting pregnant, and/or having their reputation destroyed. A woman’s deepest unconscious fear is that a man will rape or kill her. (A man’s deepest unconscious fear is that a woman will sexually humiliate him.)

Sexual Temperament Questionnaire

According to Nagoski’s research using her “Sexual Temperament Questionnaire,” 50-65% of women have a moderately strong inhibition system (SIS). Any increase in stress (anxiety, overwhelm, exhaustion) will reduce interest. And, 25% of women have a “high” SIS or a very strong braking system. These women are sensitive to all reasons not to be aroused and have more sexual problems than women with less active SIS. Nagoski says low female desire is not about hormones or boredom with monogamy; it is most likely about stress, depression, anxiety, trauma, attachment, relationship satisfaction, and lack of self-compassion. [Other researchers say boredom and lack of novelty do affect female marital desire.]

SES and SIS Operate Independently

The sensitivity of the SES and SIS are individual traits. Both can be sensitive, both can be not sensitive, and one or the other can be sensitive and not sensitive, co-existing together. (It can get very complicated!) But the general differences of dual control between men and women directly affect their sexual relating and sexual psychology. These differences are congruent with evolutionary theory and mate selection science.

Asexuals Have Essentially No Sexual Excitation System

A fairly weak accelerator (independent of brakes) is one predictor of asexuality – people who do not desire sexual contact. In studies of self-identified asexuals, researchers found asexuals had significantly “less accelerator” activity than their sexual counterparts (Prause and Graham, 2007**). Nagoski posits that part of the cause of asexuality as a sexual orientation for women is that their brains do not notice sexually relevant stimuli. Nagoski says asexuals represent only about 1 percent of the general population. Whereas, about 5-10 percent of women score as having low SES on the Sexual Temperament Questionnaire.

Why is it Important to Understand the Sexual Accelerator and Brake?

Men and women have differences that we must acknowledge and understand to have fulfilling romantic and sexual relationships.

A difference in the level of desire is the single most common sexual dysfunction for couples. Usually, that dysfunction includes a belief by one partner that their level of desire is better or is the way it “should be.” Nagoski suggests it is not the differential in desire that causes the dysfunction but how the couple manages it. The problem isn’t desire itself; it’s the context. What is needed is more sexually relevant stimuli activating the accelerator and fewer things hitting the brake.

Advice for Couples

Good advice to couples is to focus first and foremost on the operation of her “brakes.”  What is the right context for romance and sex; what context for sexual expression takes her foot off the brake? What are the sources of her stress, anxiety, and relationship dissatisfaction? What trauma is still unexamined and unresolved? What triggers her handbrake — body image concerns or worry about orgasm? The to-do list in her head?

Nagoski has a helpful worksheet in Come As You Are to identify and list the “not-so-sexy” inhibitory contexts (as well as a worksheet for situational accelerators) in the following categories: mental and physical well-being, partner characteristics, relationship characteristics, other life circumstances, and the sexual activities practiced.

Conclusion

The composition of our excitation and inhibition systems is set by our biology, life experiences, and habits. Creating the right balance of acceleration and braking for any person or couple is more art than science, and probably hard work. Again, these are individualized sensitivities. But there is no substitute for giving your partner understanding, acceptance, and compassion. Start with how men and women are generally different and what part of that difference is true for you as a person and a couple. Let’s refuel that engine with the right contexts and get it back on the road at the right speed.

Notes

See blog: Spontaneous and Response Desire — the Underbelly of Heterosexual Mating and future blogs on the importance of context for women.

*Marianne Legato is an internationally renowned academic, physician, author, lecturer, and pioneer in the field of gender-specific medicine. She is Professor Emerita of Clinical Medicine at Columba University and founder of The Partnership of Gender-Specific Medicine.

**Prause, N. and Graham, C., “Asexuality: classification and characterization.” Archives of Sexual Behavior 36, 2007, p. 341-56).

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Why More Men Than Women Die of COVID-19

Why More Men Than Women Die of COVID-19

“There are profound sex differences in immune systems and this pandemic is revealing them.”
Marcia Stefanick, Stanford University School of Medicine.

More men than women have died of the COVID-19 virus. In China, Italy, South Korea, Germany, France, Iran, the U.S – everywhere around the world, the death rate of men to women is disproportionate. In New York City, men have died at nearly twice the rate.

Death rates from COVID-19 are more evidence of the biological differences between men and women. What are the components of these differences related to the pandemic?

Habits and Comorbidity

Questions about the sex discrepancy in death rates have focused (heretofore) mostly on male behavior: higher rates of tobacco assumption, reluctance to seek medical care, and even lower rates of handwashing.

Smoking is associated with negative progression and adverse outcomes of COVID-19. Smokers are more likely to have lung disease, which is a risk factor for severe infection. Also, smokers are more likely to touch their mouths and face.

But, Sabra Klein, Professor of Molecular Microbiology and Immunology at John Hopkins* suggests that smoking is not the leading factor. “There is a growing observation of increased mortality in men across very diverse countries and cultures. When I see that, it makes me think that there must be something universal that is contributing to this.” Klein’s prior research revealed that men have lower innate antiviral immune responses to a range of infections including hepatitis C and HIV. “Their immune system may not initiate an appropriate response when it initially sees the virus.”

Men also have other “comorbidities”: higher rates of pre-existing conditions such as heart disease, high blood pressure, and diabetes. These conditions increase the risk of death from the virus.

Kathryn Sandberg, Director of the Center for the Study of Sex Differences in Health, Aging and Disease at Georgetown University, says one explanation for the disparity in COVID-19 deaths may have to do with angiotensin-converting enzyme 2 (ACE2), a protein on the surface of the cells in the lungs and other organs. ACE2 is key in regulating blood pressure and it works differently and more favorably for women. COVID-19 binds to ACE2. A study of COVID-19 patients in China found hypertension as the most common risk factor.

Overall Differences in Male and Female Lifespan and Risk of Death

We did not need a pandemic to know men live (on average) 4 years less than women; male suicide rates are much higher; significantly more men die at work and in war. We know men aged 15-25 have a vastly greater risk of injury and death. Evolutionary psychology speaks volumes about the reasons for the risky behavior of men vs. women. (It is related to androgens and mating behavior.)

In the context of a pandemic, it makes sense to remember those markers of health and longevity, but also to look deeper for underlying biological causes.

When it Comes to Survival, Men are the Weaker Sex.

Men are the weaker sex independent of a pandemic; the innate biological advantage of women is apparent at every age and stage of human life. Baby girls are more likely to make it to their first birthday. Eighty percent of all centenarians today are women; ninety-five percent of those who reach the age of 110 are women.

Female survival advantage holds regardless of education, economic factors, and alcohol, drug, or tobacco consumption.

Sandberg underscores the bottom-line: “It doesn’t matter what the infectious agent is, women tend to be better at knocking it down because they have a more robust immune system.”

Genetic Disadvantage for Males and Female Immunity

Female genetic superiority starts at the chromosomal level. The cells of genetic females have two X chromosomes. Having the use of a spare X chromosome gives females an advantage against a virus.

There are more than 2,000 genes on the two X chromosomes that interact and cooperate within a women’s body. Each cell predominantly uses one X chromosome over the other. According to physician and scientist, Sharon Moaelm*, if one X chromosome has genes that better recognize an invading virus like COVID-19, the other X chromosome that can do a different task – like killing cells infected with COVID -19. This makes the fight against the virus more efficient for women. An extra X brings extra immune functioning.

Males have to get by with just one X chromosome. If a male’s genes are not capable of recognizing or killing cells infected with the coronavirus, his ability to fight the infection will be limited. Historically, coronaviruses such as SARS and MERS tended to affect men disproportionately, according to Luis Ostrosky-Zeichner, infectious disease specialist at McGovern Medical School at UTHealth in Texas.

Since women have a greater immune response to the virus, they are quicker to reduce its viral load – the quantity of the virus. Women may also be able to launch an earlier attack on infections in general, saving the body from needing to use all of its virus-fighting capacity later.

It should be noted that women pay a cost for having a more aggressive immune system. Women are more prone to autoimmune diseases. The immune system of genetic females is more likely to attack themselves, which occurs in conditions like rheumatoid arthritis, multiple sclerosis, autoimmune thyroiditis, Sjogren’s syndrome, and lupus.

Hormonal Disadvantage for Males and Advantage for Females

Higher levels of testosterone appear to suppress the immune system. Estrogens have been found to stimulate a more vigorous immune response.

From an evolutionary perspective, some research suggests women have a stronger immune system against viral infections than men because they spend part of their lives with a “foreign body” inside of them; their baby grants them a survival advantage. Ostrosky-Zeichner believes that advantage may be related to hormonal changes.

Going Forward with Tests and Vaccine

A better understanding of men’s and women’s immune system response to the virus could be critical in developing a good vaccine. There are well-documented differences in vaccine effectiveness among men and women, with women tending to be better protected after vaccination. Therefore, it may be especially important to ensure that sex is taken into account when designing and analyzing vaccine trials.

And, as we develop antibody testing, what are the differences in the antibodies produced in men vs. women? Should the test be gender-specific? Sex differences in the immune response to COVID-19 are likely to show up in antibody surveys currently underway across the world.

Conclusion

Knowing more about how the virus differently impacts men and women could help determine the most effective treatment for individual patients. Nearly 20 years ago, the Institute of Medicine of the National Academy of Sciences published a report that claimed: “Being male or female is an important variable that should be considered.”

Moalem claims there has been little tangible progress on this insight in the practice of medicine. “We must now apprehend the real biological strength that each genetic female possesses and how men differ in this regard. The future of medicine depends upon it.”

*Sabra Klein is also President of the Organization for the Study of Sex Differences (OSSD).

**Sharon Moalem is a scientist, physician, and author. His most recent book is The Better Half: On the Genetic Superiority of Women. Moalem is an expert in the fields of rare diseases, sex differentiation, neurogenetics, and biotechnology.

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